Dgat2l6 | diacylglycerol O-acyltransferase 2-like 6

GeneMGI:3045268Synonyms: 9930021F22Rik

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Growth/size/body region Cardiovascular system Renal/urinary system

16 No significant impact

3 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:146Adult tissues
0Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetDgat2l6tm1b(KOMP)WtsihemizygoteEarly adultN/A * 
enlarged heart1 supporting datasetDgat2l6tm1b(KOMP)WtsihemizygoteEarly adultN/A * 
absent vibrissae1 supporting datasetDgat2l6tm1b(KOMP)WtsihomozygoteEarly adult7.48x10-5 
increased circulating alanine transaminase level1 supporting datasetDgat2l6tm1b(KOMP)WtsihomozygoteEarly adult4.45x10-8 
abnormal heart morphology1 supporting datasetDgat2l6tm1b(KOMP)WtsihemizygoteEarly adultN/A * 
increased circulating aspartate transaminase level1 supporting datasetDgat2l6tm1b(KOMP)WtsihomozygoteEarly adult1.45x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dgat2l6tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dgat2l6tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Dgat2l6tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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