Tgm6 | transglutaminase 6

GeneMGI:3044321Synonyms: TGM3L

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Vision/eye

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



improved glucose tolerance	1 supporting dataset	Tgm6^{tm1a(KOMP)Wtsi}	homozygote	Early adult	6.1x10^-5
increased lean body mass	1 supporting dataset	Tgm6^{tm1a(KOMP)Wtsi}	homozygote	Early adult	5.54x10^-5
decreased circulating serum albumin level	1 supporting dataset	Tgm6^{tm1a(KOMP)Wtsi}	homozygote	Early adult	9.82x10^-5
persistence of hyaloid vascular system	1 supporting dataset	Tgm6^{tm1a(KOMP)Wtsi}	homozygote	Early adult	9.55x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tgm6.

Associated images

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Histopathology

There is no histopathology data found for Tgm6.

IMPC related publications

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External links

No external links available for Tgm6.

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*Tgm6^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tgm6^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Tgm6^{tm43832(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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