Prmt8 | protein arginine N-methyltransferase 8

GeneMGI:3043083Synonyms: Hrmt1l4, Hrmt1l3

Physiological systems

20 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Vision/eye

19 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes



cataract	1 supporting dataset	Prmt8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	7.61x10^-6
abnormal lens morphology	1 supporting dataset	Prmt8^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.26x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prmt8.

Associated images

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Histopathology

There is no histopathology data found for Prmt8.

IMPC related publications

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External links

No external links available for Prmt8.

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*Prmt8^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Prmt8^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Prmt8^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Prmt8^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Prmt8^{tm43072(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes