Nfkbid | nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging
16 No significant impact
4 Not tested
Data collections
Viability data
Body weight measurements
Embryo imaging data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased NK cell number | 1 supporting dataset | Nfkbidtm1a(EUCOMM)Wtsi | heterozygote | Early adult | 3.89x10-5 | ||
increased CD8-positive, alpha-beta T cell number | 1 supporting dataset | Nfkbidtm1a(EUCOMM)Wtsi | heterozygote | Early adult | 4.61x10-6 | ||
decreased B cell number | 1 supporting dataset | Nfkbidtm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.05x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Nfkbidtm1a(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
decreased circulating triglyceride level | 1 supporting dataset | Nfkbidtm1a(EUCOMM)Wtsi | heterozygote | Early adult | 1.52x10-5 |
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External links
No external links available for Nfkbid.
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Nfkbidtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
Nfkbidtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
Nfkbidtm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |
Nfkbidtm44655(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |