Nfkbid | nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta

GeneMGI:3041243Synonyms: IkappaBNS

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased NK cell number1 supporting datasetNfkbidtm1a(EUCOMM)WtsiheterozygoteEarly adult3.89x10-5 
increased CD8-positive, alpha-beta T cell number1 supporting datasetNfkbidtm1a(EUCOMM)WtsiheterozygoteEarly adult4.61x10-6 
decreased B cell number1 supporting datasetNfkbidtm1a(EUCOMM)WtsiheterozygoteEarly adult1.05x10-5 
preweaning lethality, complete penetrance1 supporting datasetNfkbidtm1a(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased circulating triglyceride level1 supporting datasetNfkbidtm1a(EUCOMM)WtsiheterozygoteEarly adult1.52x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Nfkbidtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Nfkbidtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Nfkbidtm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Nfkbidtm44655(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter