Adgrd1 | adhesion G protein-coupled receptor D1

GeneMGI:3041203Synonyms: E230012M21Rik, Gpr133

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Immune system Skeleton

15 No significant impact

6 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

female infertility1 supporting datasetAdgrd1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased anti-nuclear antigen antibody level4 supporting datasetsAdgrd1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
decreased bone mineral density1 supporting datasetAdgrd1tm1b(EUCOMM)WtsihomozygoteEarly adult3.16x10-5 
decreased bone mineral content1 supporting datasetAdgrd1tm1b(EUCOMM)WtsihomozygoteEarly adult2.61x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Adgrd1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Adgrd1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Adgrd1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Adgrd1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Adgrd1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Adgrd1tm45840(L1L2_st1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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