Lca5l | Leber congenital amaurosis 5-like
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Vision/eye Hematopoietic system
14 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased erythrocyte cell number | 1 supporting dataset | Lca5lem1(IMPC)Ics | homozygote | Early adult | 6.29x10-5 | ||
| decreased hemoglobin content | 1 supporting dataset | Lca5lem1(IMPC)Ics | homozygote | Early adult | 9.42x10-5 | ||
| decreased hematocrit | 1 supporting dataset | Lca5lem1(IMPC)Ics | homozygote | Early adult | 9.6x10-5 | ||
| male infertility | 1 supporting dataset | Lca5lem1(IMPC)Ics | homozygote | Early adult | N/A * | ||
| increased circulating bilirubin level | 1 supporting dataset | Lca5lem1(IMPC)Ics | homozygote | Early adult | 4.42x10-10 | ||
| thrombocytopenia | 1 supporting dataset | Lca5lem1(IMPC)Ics | homozygote | Early adult | 3.6x10-6 | ||
| increased total retina thickness | 2 supporting datasets | Lca5lem1(IMPC)Ics | homozygote | Early adult | 2.03x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Lca5lem1(IMPC)Ics | homozygote | Early adult | 2.07x10-5 |
| | | | | | | | | | |
External links
No external links available for Lca5l.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Lca5lem1(IMPC)Ics | Deletion | | mouse |