Zbtb24 | zinc finger and BTB domain containing 24

GeneMGI:3039618Synonyms: ZNF450

Physiological systems

19 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

13 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina blood vessel morphology	1 supporting dataset	Zbtb24^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	8.58x10^-8
abnormal lens morphology	2 supporting datasets	Zbtb24^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.72x10^-6
abnormal retina vasculature morphology	1 supporting dataset	Zbtb24^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	9.66x10^-6
increased circulating HDL cholesterol level	1 supporting dataset	Zbtb24^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	7.55x10^-5
decreased red blood cell distribution width	1 supporting dataset	Zbtb24^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	2.05x10^-5
decreased circulating chloride level	1 supporting dataset	Zbtb24^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	4.85x10^-6
increased startle reflex	1 supporting dataset	Zbtb24^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.44x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Zbtb24^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Zbtb24.

Associated images

Loading...

Histopathology

There is no histopathology data found for Zbtb24.

IMPC related publications

Loading...

External links

No external links available for Zbtb24.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Zbtb24^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Zbtb24^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Zbtb24^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

My Genes