Timd6 | T cell immunoglobulin and mucin domain containing 6

GeneMGI:3039605Synonyms: BC053393

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

trunk curl1 supporting datasetTimd6tm1b(KOMP)WtsiheterozygoteEarly adult5.31x10-13 
decreased lymphocyte cell number1 supporting datasetTimd6tm1b(KOMP)WtsiheterozygoteEarly adult1.56x10-5 
increased neutrophil cell number1 supporting datasetTimd6tm1b(KOMP)WtsiheterozygoteEarly adult1.45x10-6 
increased spleen weight1 supporting datasetTimd6tm1b(KOMP)WtsiheterozygoteEarly adult1.16x10-6 
preweaning lethality, complete penetrance1 supporting datasetTimd6tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Timd6tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Timd6tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Timd6tm37731(L1L2_st0)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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