Kcna10 | potassium voltage-gated channel, shaker-related subfamily, member 10

GeneMGI:3037820Synonyms: Kcna8, Kv1.8

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Immune system Growth/size/body region Hematopoietic system Mortality/aging

17 No significant impact

3 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetKcna10em3(IMPC)MbpheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance3 supporting datasetsKcna10em3(IMPC)MbphomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetKcna10em3(IMPC)MbphomozygoteE12.5N/A * 
abnormal spleen morphology1 supporting datasetKcna10em3(IMPC)MbpheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kcna10em2(IMPC)MbpExon Deletionmouse
Kcna10em3(IMPC)MbpIndelmouse
Kcna10tm113552(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Kcna10tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Kcna10tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Kcna10tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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