Zfp532 | zinc finger protein 532

GeneMGI:3036282Synonyms: C530030I18Rik

Physiological systems

13 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Mortality/aging

10 No significant impact

11 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

thrombocytosis1 supporting datasetZfp532em1(IMPC)JheterozygoteEarly adult9.37x10-12 
increased erythrocyte cell number1 supporting datasetZfp532em1(IMPC)JheterozygoteEarly adult3.5x10-5 
increased circulating HDL cholesterol level1 supporting datasetZfp532em1(IMPC)JheterozygoteEarly adult8.74x10-5 
decreased circulating alanine transaminase level1 supporting datasetZfp532em1(IMPC)JheterozygoteEarly adult8.12x10-5 
decreased circulating aspartate transaminase level1 supporting datasetZfp532em1(IMPC)JheterozygoteEarly adult7.4x10-8 
decreased mean corpuscular volume1 supporting datasetZfp532em1(IMPC)JheterozygoteEarly adult6.97x10-5 
preweaning lethality, complete penetrance1 supporting datasetZfp532em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp532em1(IMPC)JIntra-exon deletionmouse
Zfp532tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Zfp532tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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