Atxn7l3 | ataxin 7-like 3
Physiological systems
19 / 24 physiological systems tested
8 Significantly impacted by the knock-out
Pigmentation Integument Limbs/digits/tail Vision/eye Behavior/neurological Skeleton Cardiovascular system Mortality/aging
11 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
short tibia | 2 supporting datasets | Atxn7l3tm1.1(KOMP)Wtsi | heterozygote | Early adult | 1.33x10-7 | ||
decreased total retina thickness | 1 supporting dataset | Atxn7l3tm1.1(KOMP)Wtsi | heterozygote | Early adult | 3.89x10-5 | ||
abnormal retina vasculature morphology | 1 supporting dataset | Atxn7l3tm1.1(KOMP)Wtsi | heterozygote | Early adult | 4.22x10-9 | ||
abnormal vocalization | 1 supporting dataset | Atxn7l3tm1.1(KOMP)Wtsi | heterozygote | Early adult | 2.45x10-5 | ||
abnormal retina blood vessel morphology | 1 supporting dataset | Atxn7l3tm1.1(KOMP)Wtsi | heterozygote | Early adult | 4.18x10-9 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Atxn7l3tm1.1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
abnormal coat/hair pigmentation | 1 supporting dataset | Atxn7l3tm1.1(KOMP)Wtsi | heterozygote | Early adult | 9.02x10-5 |
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External links
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Atxn7l3tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Atxn7l3tm1.1(KOMP)Wtsi | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Atxn7l3tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | mouse |
Atxn7l3tm210450(L1L2_Pgk_P) | Reporter-tagged deletion allele (with selection cassette) | | targeting vector |