Tmtc3 | transmembrane and tetratricopeptide repeat containing 3
Physiological systems
21 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Mortality/aging Cardiovascular system
19 No significant impact
3 Not tested
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Tmtc3tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal sinus arrhythmia | 1 supporting dataset | Tmtc3tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 7.83x10-5 | ||
| increased heart rate variability | 1 supporting dataset | Tmtc3tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 8.87x10-8 |
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External links
No external links available for Tmtc3.
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| Tmtc3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Tmtc3tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Tmtc3tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Tmtc3tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |