Hdac4 | histone deacetylase 4

GeneMGI:3036234Synonyms: 4932408F19Rik

Physiological systems

23 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Behavior/neurological

19 No significant impact

1 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



no spontaneous movement	1 supporting dataset	Hdac4^{em1(IMPC)Ccpcz}	homozygote	E18.5	N/A ^*
increased circulating alkaline phosphatase level	1 supporting dataset	Hdac4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	5.19x10^-6
increased NK cell number	1 supporting dataset	Hdac4^{em1(IMPC)Ccpcz}	heterozygote	Early adult	8.09x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hdac4.

Associated images

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Histopathology

There is no histopathology data found for Hdac4.

IMPC related publications

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External links

No external links available for Hdac4.

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*Hdac4^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Hdac4^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Hdac4^tm1aNarl*	KO first allele (reporter-tagged insertion with conditional potential)	‌	es cell

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