Rasgrp3 | RAS, guanyl releasing protein 3

GeneMGI:3028579Synonyms: LOC240168

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Reproductive system Immune system Vision/eye Hematopoietic system Behavior/neurological

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetRasgrp3em1(IMPC)WtsihomozygoteEarly adultN/A * 
enhanced contextual conditioning behavior1 supporting datasetRasgrp3em1(IMPC)WtsihomozygoteEarly adult7.75x10-5 
decreased mean corpuscular hemoglobin1 supporting datasetRasgrp3em1(IMPC)WtsihomozygoteEarly adult1.55x10-5 
decreased mean platelet volume1 supporting datasetRasgrp3em1(IMPC)WtsihomozygoteEarly adult8.48x10-13 
increased CD8-positive, naive alpha-beta T cell number1 supporting datasetRasgrp3em1(IMPC)WtsihomozygoteEarly adult2.43x10-8 
abnormal uterus morphology1 supporting datasetRasgrp3em1(IMPC)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rasgrp3em1(IMPC)WtsiExon Deletionmouse
Rasgrp3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Rasgrp3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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