Dhx37 | DEAH-box helicase 37

GeneMGI:3028576Synonyms: LOC381671, LOC208144

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
5Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetDhx37em1(IMPC)JheterozygoteEarly adult3.12x10-5 
increased grip strength1 supporting datasetDhx37em1(IMPC)JheterozygoteEarly adult9.83x10-6 
embryonic lethality prior to organogenesis1 supporting datasetDhx37em1(IMPC)JhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetDhx37em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dhx37em1(IMPC)JExon Deletionmouse
Dhx37tm171111(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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