Ppp4r2 | protein phosphatase 4, regulatory subunit 2

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging Renal/urinary system

16 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:76Adult tissues
25Embryo tissues

Phenotypes

abnormal kidney morphology1 supporting datasetPpp4r2tm2b(EUCOMM)HmguheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetPpp4r2tm2b(EUCOMM)HmguhomozygoteEarly adultN/A * 
hyperactivity3 supporting datasetsPpp4r2tm2b(EUCOMM)HmguheterozygoteEarly adult1.71x10-6 
increased exploration in new environment1 supporting datasetPpp4r2tm2b(EUCOMM)HmguheterozygoteEarly adult5.64x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ppp4r2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ppp4r2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Ppp4r2tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ppp4r2tm2b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Ppp4r2tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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