Ino80d | INO80 complex subunit D

GeneMGI:3027003Synonyms: A430093A21Rik

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Adipose tissue Embryo Growth/size/body region Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

62Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	3 supporting datasets	Ino80d^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased locomotor activity	3 supporting datasets	Ino80d^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	6.83x10^-6
increased lean body mass	2 supporting datasets	Ino80d^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.33x10^-6
decreased total body fat amount	2 supporting datasets	Ino80d^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	4.08x10^-7
decreased total retina thickness	2 supporting datasets	Ino80d^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	8.12x10^-8
abnormal embryo size	1 supporting dataset	Ino80d^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Ino80d^{tm1b(EUCOMM)Wtsi}	homozygote	E18.5	N/A ^*
abnormal retina outer nuclear layer morphology	2 supporting datasets	Ino80d^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.02x10^-9

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ino80d.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ino80d.

IMPC related publications

Loading...

External links

No external links available for Ino80d.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ino80d^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ino80d^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ino80d^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ino80d^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Ino80d^{tm33693(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes