Zc3h12c | zinc finger CCCH type containing 12C

GeneMGI:3026959Synonyms: C230027N18Rik

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Skeleton

13 No significant impact

7 Not tested

Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes2 supporting datasetsZc3h12cem1(IMPC)TcphomozygoteEarly adultN/A * 
increased circulating triglyceride level1 supporting datasetZc3h12cem1(IMPC)TcphomozygoteEarly adult8.38x10-5 
decreased lymphocyte cell number1 supporting datasetZc3h12cem1(IMPC)TcphomozygoteEarly adult5.64x10-6 
decreased bone mineral density1 supporting datasetZc3h12cem1(IMPC)TcphomozygoteEarly adult4.75x10-5 
increased neutrophil cell number1 supporting datasetZc3h12cem1(IMPC)TcphomozygoteEarly adult3.08x10-6 
decreased bone mineral content1 supporting datasetZc3h12cem1(IMPC)TcphomozygoteEarly adult8.13x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zc3h12cem1(IMPC)TcpExon Deletionmouse
Zc3h12ctm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Zc3h12ctm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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