Kash5 | KASH domain containing 5

GeneMGI:2687329Synonyms: LOC384619, Ccdc155

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	2 supporting datasets	Kash5^em1(IMPC)J	homozygote	Early adult	1.58x10^-11
abnormal bone structure	1 supporting dataset	Kash5^em1(IMPC)J	homozygote	Early adult	6.18x10^-11
increased total body fat amount	2 supporting datasets	Kash5^em1(IMPC)J	homozygote	Early adult	1.23x10^-12
female infertility	1 supporting dataset	Kash5^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased leukocyte cell number	1 supporting dataset	Kash5^em1(IMPC)J	homozygote	Early adult	2.55x10^-6
increased circulating HDL cholesterol level	1 supporting dataset	Kash5^em1(IMPC)J	homozygote	Early adult	1.72x10^-5
decreased locomotor activity	1 supporting dataset	Kash5^em1(IMPC)J	homozygote	Early adult	8.65x10^-6
decreased bone mineral content	2 supporting datasets	Kash5^em1(IMPC)J	homozygote	Early adult	4.95x10^-21
decreased bone mineral density	1 supporting dataset	Kash5^em1(IMPC)J	homozygote	Early adult	2.47x10^-16
male infertility	1 supporting dataset	Kash5^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Kash5.

Associated images

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Histopathology

There is no histopathology data found for Kash5.

IMPC related publications

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External links

No external links available for Kash5.

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*Kash5^em1(IMPC)J*	Exon Deletion	‌	mouse
*Kash5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Kash5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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