Ano8 | anoctamin 8
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Behavior/neurological Skeleton
12 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| impaired righting response | 1 supporting dataset | Ano8em1(IMPC)J | homozygote | Late adult | 1.3x10-5 | ||
| hyperactivity | 1 supporting dataset | Ano8em1(IMPC)J | heterozygote | Early adult | 4.04x10-5 | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Ano8em1(IMPC)J | homozygote | Late adult | 6.08x10-5 | ||
| abnormal locomotor behavior | 1 supporting dataset | Ano8em1(IMPC)J | homozygote | Late adult | 3.07x10-6 | ||
| decreased bone mineral content | 2 supporting datasets | Ano8em1(IMPC)J | heterozygote | Early adult | 2.2x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Ano8em1(IMPC)J | homozygote | Late adult | 4.83x10-5 |
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External links
No external links available for Ano8.
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| Ano8em1(IMPC)J | Exon Deletion | | mouse |
| Ano8tm290068(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |