Inpp5a | inositol polyphosphate-5-phosphatase A
GeneMGI:2686961
Physiological systems
20 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Integument Adipose tissue Embryo Growth/size/body region Mortality/aging
14 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| pallor | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | heterozygote | E15.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Inpp5aem1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| edema | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | heterozygote | E15.5 | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | heterozygote | Early adult | 3.77x10-5 | ||
| edema | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal skin coloration | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | homozygote | E15.5 | N/A * | ||
| decreased lean body mass | 1 supporting dataset | Inpp5aem1(IMPC)Tcp | heterozygote | Early adult | 7.27x10-6 |
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External links
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| Inpp5aem1(IMPC)Tcp | Exon Deletion | | mouse |
| Inpp5atm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Inpp5atm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |