Zfhx2 | zinc finger homeobox 2

GeneMGI:2686934Synonyms: zfh-5

Physiological systems

11 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Reproductive system Behavior/neurological Skeleton

8 No significant impact

13 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vertebral arch morphology2 supporting datasetsZfhx2em1(IMPC)RbrchomozygoteEarly adult2.39x10-6 
decreased anxiety-related response1 supporting datasetZfhx2em1(IMPC)RbrchomozygoteEarly adult3.08x10-8 
abnormal behavior1 supporting datasetZfhx2em1(IMPC)RbrchomozygoteEarly adult5.47x10-5 
abnormal epididymis morphology1 supporting datasetZfhx2em1(IMPC)RbrchomozygoteEarly adultN/A * 
decreased thigmotaxis2 supporting datasetsZfhx2em1(IMPC)RbrchomozygoteEarly adult1.7x10-5 
hyperactivity2 supporting datasetsZfhx2em1(IMPC)RbrchomozygoteEarly adult4.76x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfhx2em1(IMPC)RbrcExon Deletionmouse
Zfhx2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Zfhx2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Zfhx2tm261548(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Zfhx2tm407023(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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