Bbs12 | Bardet-Biedl syndrome 12
Physiological systems
24 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging
17 No significant impact
Data collections
Gene metrics:8Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged spleen | 1 supporting dataset | Bbs12em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal spleen morphology | 2 supporting datasets | Bbs12em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| enlarged heart | 1 supporting dataset | Bbs12em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| no spontaneous movement | 1 supporting dataset | Bbs12em1(IMPC)Ccpcz | homozygote | E18.5 | N/A * | ||
| abnormal thymus morphology | 1 supporting dataset | Bbs12em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Bbs12em1(IMPC)Ccpcz | homozygote | Early adult | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Bbs12em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| enlarged thymus | 1 supporting dataset | Bbs12em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * |
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External links
No external links available for Bbs12.
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| Bbs12em1(IMPC)Ccpcz | Inter-exon deletion | | mouse |
| Bbs12tm213523(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |