Aim2 | absent in melanoma 2

GeneMGI:2686159Synonyms: LOC383619, Ifi210

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Hematopoietic system

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged spleen1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged thymus1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal thymus morphology1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased circulating total protein level1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adult3.03x10-7 
abnormal spleen morphology1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
enlarged gallbladder1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
abnormal gallbladder morphology1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adultN/A * 
increased circulating serum albumin level1 supporting datasetAim2em1(IMPC)CcpczhomozygoteEarly adult8.18x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aim2em1(IMPC)CcpczExon Deletionmouse
Aim2tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Aim2tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Aim2tm358829(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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