Cib3 | calcium and integrin binding family member 3

GeneMGI:2685953Synonyms: KIP3, C730014M21Rik

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Hearing/vestibular/ear Vision/eye Behavior/neurological

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

absent vibrissae1 supporting datasetCib3em1(IMPC)HhomozygoteLate adult2.11x10-6 
decreased locomotor activity6 supporting datasetsCib3em1(IMPC)HhomozygoteEarly adult1.28x10-7 
decreased exploration in new environment1 supporting datasetCib3em1(IMPC)HhomozygoteEarly adult1.45x10-9 
trunk curl1 supporting datasetCib3em1(IMPC)HhomozygoteMiddle aged adult1.91x10-8 
cataract1 supporting datasetCib3em1(IMPC)HhomozygoteEarly adult1.76x10-5 
increased circulating amylase level1 supporting datasetCib3em1(IMPC)HhomozygoteLate adult9.11x10-5 
abnormal ear morphology1 supporting datasetCib3em1(IMPC)HhomozygoteEarly adult7.75x10-7 
trunk curl1 supporting datasetCib3em1(IMPC)HhomozygoteLate adult1.74x10-11 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cib3em1(IMPC)HExon Deletionmouse
Cib3em2(IMPC)HExon Deletionmouse
Cib3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Cib3tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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