Prdm12 | PR domain containing 12
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Behavior/neurological Mortality/aging Cardiovascular system
13 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
51Embryo tissues
| decreased locomotor activity | 4 supporting datasets | Prdm12tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 1.13x10-5 | ||
| shortened QRS complex duration | 1 supporting dataset | Prdm12tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 2.56x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Prdm12tm2b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Prdm12tm2b(EUCOMM)Hmgu | heterozygote | E15.5 | N/A * | ||
| increased circulating cholesterol level | 1 supporting dataset | Prdm12tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 9.02x10-5 | ||
| decreased exploration in new environment | 2 supporting datasets | Prdm12tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 3.23x10-12 |
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External links
No external links available for Prdm12.
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| Prdm12tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Prdm12tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Prdm12tm2b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Prdm12tm2e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Prdm12tm39295(L1L2_gt1) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |