Nsl1 | NSL1, MIS12 kinetochore complex component

GeneMGI:2685830Synonyms: 4833432M17Rik, LOC381318

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased leukocyte cell number	1 supporting dataset	Nsl1^em1(IMPC)J	heterozygote	Early adult	2.92x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Nsl1^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Nsl1^em1(IMPC)J	heterozygote	Early adult	2.05x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Nsl1^em1(IMPC)J	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nsl1.

Associated images

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Histopathology

There is no histopathology data found for Nsl1.

IMPC related publications

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External links

No external links available for Nsl1.

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*Nsl1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Nsl1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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