Hecw2 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2

GeneMGI:2685817Synonyms: Nedl2, A730039N16Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Mortality/aging

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:1Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes



preweaning lethality, incomplete penetrance	1 supporting dataset		Hecw2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult		N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hecw2.

Associated images

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Histopathology

There is no histopathology data found for Hecw2.

IMPC related publications

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External links

No external links available for Hecw2.

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*Hecw2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Hecw2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Hecw2^{tm47316(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes