Hpse2 | heparanase 2

GeneMGI:2685814

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



impaired pupillary reflex	1 supporting dataset	Hpse2^em1(IMPC)J	heterozygote	Early adult	7.35x10^-8
preweaning lethality, incomplete penetrance	1 supporting dataset	Hpse2^em1(IMPC)J	homozygote	Early adult	N/A ^*
cataract	1 supporting dataset	Hpse2^em1(IMPC)J	heterozygote	Early adult	6.36x10^-5
hyperactivity	1 supporting dataset	Hpse2^em1(IMPC)J	heterozygote	Early adult	9.65x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Hpse2.

Associated images

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Histopathology

There is no histopathology data found for Hpse2.

IMPC related publications

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External links

No external links available for Hpse2.

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*Hpse2^em1(IMPC)J*	Exon Deletion	‌	mouse
*Hpse2^{tm370744(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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