Spata22 | spermatogenesis associated 22

GeneMGI:2685728Synonyms: LOC380709

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Reproductive system Endocrine/exocrine gland Skeleton

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal testis morphology	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
female infertility	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
small testis	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
male infertility	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
abnormal bone structure	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.43x10^-5
decreased bone mineral content	2 supporting datasets	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.98x10^-11
decreased bone mineral density	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.27x10^-18
abnormal pancreas morphology	1 supporting dataset	Spata22^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Spata22.

Associated images

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Histopathology

There is no histopathology data found for Spata22.

IMPC related publications

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External links

No external links available for Spata22.

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*Spata22^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Spata22^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Spata22^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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