Clec3a | C-type lectin domain family 3, member a

GeneMGI:2685642Synonyms: 1110019O10Rik, LOC330844, +1 more

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Integument Adipose tissue Growth/size/body region Hearing/vestibular/ear Behavior/neurological Skeleton

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased total body fat amount2 supporting datasetsClec3aem1(IMPC)JhomozygoteEarly adult2.7x10-8 
hyperactivity1 supporting datasetClec3aem1(IMPC)JhomozygoteEarly adult7.31x10-6 
increased lean body mass1 supporting datasetClec3aem1(IMPC)JhomozygoteEarly adult4.6x10-8 
absent vibrissae1 supporting datasetClec3aem1(IMPC)JhomozygoteEarly adult1.67x10-5 
abnormal auditory brainstem response1 supporting datasetClec3aem1(IMPC)JhomozygoteEarly adult1.6x10-5 
increased bone mineral density1 supporting datasetClec3aem1(IMPC)JhomozygoteEarly adult3.89x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Clec3aem1(IMPC)JExon Deletionmouse

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