Drc7 | dynein regulatory complex subunit 7

GeneMGI:2685616Synonyms: LOC330830, SRG-L, +1 more

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Pigmentation Integument Behavior/neurological Cardiovascular system

11 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength2 supporting datasetsDrc7em1(IMPC)JhomozygoteEarly adult5.65x10-6 
male infertility1 supporting datasetDrc7em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal sinus arrhythmia1 supporting datasetDrc7em1(IMPC)JhomozygoteLate adult2x10-5 
increased circulating alkaline phosphatase level1 supporting datasetDrc7em1(IMPC)JhomozygoteLate adult1.29x10-5 
abnormal coat/hair pigmentation1 supporting datasetDrc7em1(IMPC)JhomozygoteLate adult3.11x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Drc7em1(IMPC)JExon Deletionmouse
Drc7tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Drc7tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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