Cyb5d1 | cytochrome b5 domain containing 1

GeneMGI:2685586Synonyms: LOC327951

Physiological systems

17 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Skeleton Craniofacial

8 No significant impact

7 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
46Embryo tissues

Phenotypes

decreased circulating free fatty acids level1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult3.33x10-6 
convulsive seizures1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult5.41x10-6 
increased circulating sodium level1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult7.77x10-6 
abnormal tooth morphology2 supporting datasetsCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult3.36x10-5 
decreased circulating serum albumin level1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult7.81x10-6 
abnormal startle reflex1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult5.27x10-5 
hyperactivity2 supporting datasetsCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult1.56x10-5 
decreased total body fat amount1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult3.65x10-5 
increased circulating alkaline phosphatase level1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult2.17x10-5 
increased leukocyte cell number1 supporting datasetCyb5d1tm1.1(KOMP)VlcghomozygoteEarly adult2.74x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cyb5d1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Cyb5d1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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