Hsf5 | heat shock transcription factor family member 5

GeneMGI:2685585Synonyms: LOC327992

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Adipose tissue Growth/size/body region Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetHsf5em1(IMPC)JhomozygoteEarly adultN/A * 
decreased lean body mass2 supporting datasetsHsf5em1(IMPC)JhomozygoteEarly adult1.14x10-7 
increased total body fat amount2 supporting datasetsHsf5em1(IMPC)JhomozygoteEarly adult2.63x10-7 
increased fasting circulating glucose level1 supporting datasetHsf5em1(IMPC)JhomozygoteEarly adult3.66x10-5 
decreased heart rate1 supporting datasetHsf5em1(IMPC)JhomozygoteEarly adult9.04x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hsf5em1(IMPC)JExon Deletionmouse
Hsf5tm61(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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