Dnai2 | dynein axonemal intermediate chain 2

GeneMGI:2685574Synonyms: C030015H18Rik, Dnaic2, +1 more

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Adipose tissue Growth/size/body region Mortality/aging Renal/urinary system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Dnai2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
increased total body fat amount	2 supporting datasets	Dnai2^em1(IMPC)Tcp	heterozygote	Early adult	8.42x10^-6
enlarged urinary bladder	1 supporting dataset	Dnai2^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
enlarged lymph nodes	1 supporting dataset	Dnai2^em1(IMPC)Tcp	heterozygote	Early adult	N/A ^*
decreased lean body mass	2 supporting datasets	Dnai2^em1(IMPC)Tcp	heterozygote	Early adult	1.71x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Dnai2.

Associated images

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Histopathology

There is no histopathology data found for Dnai2.

IMPC related publications

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External links

No external links available for Dnai2.

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*Dnai2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Dnai2^{tm134(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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