Ajap1 | adherens junction associated protein 1

GeneMGI:2685419Synonyms: LOC230959

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Skeleton

15 No significant impact

6 Not tested

Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
47Embryo tissues

Phenotypes

increased circulating alanine transaminase level1 supporting datasetAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult4.48x10-10 
hyperactivity8 supporting datasetsAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult2.28x10-13 
decreased bone mineral content2 supporting datasetsAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult3.93x10-8 
decreased thigmotaxis2 supporting datasetsAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult9.7x10-5 
increased circulating sodium level1 supporting datasetAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult1.82x10-11 
abnormal bone structure1 supporting datasetAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult3.58x10-13 
increased circulating aspartate transaminase level1 supporting datasetAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult6x10-5 
increased circulating total protein level1 supporting datasetAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult6.71x10-5 
abnormal behavior1 supporting datasetAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult9.71x10-5 
increased circulating chloride level1 supporting datasetAjap1tm1b(EUCOMM)HmguhomozygoteEarly adult3.09x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ajap1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ajap1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Ajap1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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