Trim56 | tripartite motif-containing 56

GeneMGI:2685298Synonyms: LOC384309, RNF109, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating HDL cholesterol level	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.83x10^-6
decreased circulating iron level	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.47x10^-6
increased grip strength	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.06x10^-5
decreased regulatory T cell number	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
increased circulating iron level	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.76x10^-6
decreased circulating cholesterol level	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	6.28x10^-6
decreased body length	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.03x10^-6
decreased circulating glucose level	1 supporting dataset	Trim56^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.73x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Trim56.

Associated images

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Histopathology

There is no histopathology data found for Trim56.

IMPC related publications

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External links

No external links available for Trim56.

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*Trim56^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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