Kbtbd7 | kelch repeat and BTB (POZ) domain containing 7

GeneMGI:2685141Synonyms: LOC211255, 1110008P08Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Skeleton

14 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
50Embryo tissues

Phenotypes

hyperactivity8 supporting datasetsKbtbd7tm1.1(KOMP)VlcghomozygoteEarly adult1.93x10-45 
abnormal behavior1 supporting datasetKbtbd7tm1.1(KOMP)VlcghomozygoteEarly adult9.98x10-13 
decreased grip strength1 supporting datasetKbtbd7tm1.1(KOMP)VlcghomozygoteEarly adult7.02x10-5 
increased circulating bilirubin level1 supporting datasetKbtbd7tm1.1(KOMP)VlcghomozygoteEarly adult7.94x10-7 
decreased thigmotaxis2 supporting datasetsKbtbd7tm1.1(KOMP)VlcghomozygoteEarly adult9.88x10-13 
abnormal bone structure1 supporting datasetKbtbd7tm1.1(KOMP)VlcghomozygoteEarly adult4.59x10-7 
decreased bone mineral content1 supporting datasetKbtbd7tm1.1(KOMP)VlcghomozygoteEarly adult1.63x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Kbtbd7tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Kbtbd7tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Kbtbd7tm444628(Ifitm2_intron_L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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