Hmcn1 | hemicentin 1

GeneMGI:2685047Synonyms: EG545370, LOC240793

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Vision/eye Behavior/neurological

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

cataract1 supporting datasetHmcn1em1(IMPC)JhomozygoteEarly adult1.45x10-8 
abnormal optic disk morphology1 supporting datasetHmcn1em1(IMPC)JhomozygoteEarly adult1.4x10-7 
hyperactivity1 supporting datasetHmcn1em1(IMPC)JhomozygoteEarly adult5.35x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Hmcn1em1(IMPC)JExon Deletionmouse
Hmcn1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Hmcn1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Hmcn1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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