Ascl5 | achaete-scute family bHLH transcription factor 5

GeneMGI:2685043Synonyms: AmeloD, LOC226439, +2 more

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Endocrine/exocrine gland Integument Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal heart morphology	1 supporting dataset	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	2 supporting datasets	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating total protein level	1 supporting dataset	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	9.56x10^-5
enlarged heart	1 supporting dataset	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
increased circulating creatine kinase level	1 supporting dataset	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.06x10^-6
abnormal thymus morphology	1 supporting dataset	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	1 supporting dataset	Ascl5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ascl5.

Associated images

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Histopathology

There is no histopathology data found for Ascl5.

IMPC related publications

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External links

No external links available for Ascl5.

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*Ascl5^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse

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