Cog7 | component of oligomeric golgi complex 7

GeneMGI:2685013Synonyms: 5630400E24Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Cardiovascular system Mortality/aging

14 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

abnormal sinus arrhythmia1 supporting datasetCog7tm1b(EUCOMM)HmguheterozygoteEarly adult8.14x10-5 
embryonic lethality prior to organogenesis1 supporting datasetCog7tm1b(EUCOMM)HmguhomozygoteE9.5N/A * 
impaired pupillary reflex1 supporting datasetCog7tm1b(EUCOMM)HmguheterozygoteEarly adult5.43x10-6 
preweaning lethality, complete penetrance1 supporting datasetCog7tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
cornea deposits1 supporting datasetCog7tm1b(EUCOMM)HmguheterozygoteEarly adult4.95x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cog7tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Cog7tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cog7tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cog7tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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