Lclat1 | lysocardiolipin acyltransferase 1

GeneMGI:2684937Synonyms: Lycat, ALCAT1, +1 more

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating alkaline phosphatase level1 supporting datasetLclat1em1(IMPC)MbphomozygoteEarly adult6.2x10-8 
increased mean corpuscular hemoglobin1 supporting datasetLclat1em1(IMPC)MbphomozygoteEarly adult4.91x10-6 
increased mean corpuscular volume1 supporting datasetLclat1em1(IMPC)MbphomozygoteEarly adult5.67x10-9 
increased circulating alanine transaminase level1 supporting datasetLclat1em1(IMPC)MbphomozygoteEarly adult1.9x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lclat1em1(IMPC)MbpExon Deletionmouse

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