Gxylt1 | glucoside xylosyltransferase 1

GeneMGI:2684933Synonyms: LOC382997, LOC223827, +1 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Nervous system Cardiovascular system Mortality/aging

14 No significant impact

5 Not tested

Gene metrics:11Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to tooth bud stage1 supporting datasetGxylt1em1(IMPC)BayhomozygoteE12.5N/A * 
abnormal vitelline vasculature morphology1 supporting datasetGxylt1em1(IMPC)BayhomozygoteE9.5N/A * 
abnormal forebrain development1 supporting datasetGxylt1em1(IMPC)BayhomozygoteE9.5N/A * 
pale yolk sac1 supporting datasetGxylt1em1(IMPC)BayhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetGxylt1em1(IMPC)BayhomozygoteEarly adultN/A * 
abnormal neural tube morphology1 supporting datasetGxylt1em1(IMPC)BayhomozygoteE9.5N/A * 
edema1 supporting datasetGxylt1em1(IMPC)BayhomozygoteE9.5N/A * 
prolonged PR interval1 supporting datasetGxylt1em1(IMPC)BayheterozygoteEarly adult7.27x10-5 
abnormal visceral yolk sac morphology1 supporting datasetGxylt1em1(IMPC)BayhomozygoteE9.5N/A * 
preweaning lethality, incomplete penetrance2 supporting datasetsGxylt1em1(IMPC)BayhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gxylt1em1(IMPC)BayExon Deletionmouse
Gxylt1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gxylt1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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