Zfp469 | zinc finger protein 469

GeneMGI:2684868Synonyms: Gm22, LOC195209

Physiological systems

20 / 24 physiological systems tested

10 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hearing/vestibular/ear Vision/eye Hematopoietic system Behavior/neurological Renal/urinary system

10 No significant impact

4 Not tested

Gene metrics:11Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal vitreous body morphology1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adult3.94x10-7 
enlarged kidney1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal auditory brainstem response3 supporting datasetsZfp469em1(IMPC)MbphomozygoteEarly adult1.83x10-6 
increased leukocyte cell number1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adult9.39x10-7 
abnormal kidney morphology1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating alkaline phosphatase level1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adult6.99x10-5 
increased lymphocyte cell number1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adult5.67x10-12 
decreased grip strength1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adult2.41x10-5 
abnormal seminal vesicle morphology1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adultN/A * 
cataract1 supporting datasetZfp469em1(IMPC)MbphomozygoteEarly adult3.08x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp469em1(IMPC)MbpIntra-exon deletionmouse

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