Pfas | phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Pigmentation Integument Growth/size/body region Mortality/aging Craniofacial
12 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal snout morphology | 1 supporting dataset | Pfasem1(IMPC)J | heterozygote | Early adult | 1.98x10-7 | ||
| abnormal nail morphology | 1 supporting dataset | Pfasem1(IMPC)J | heterozygote | Early adult | 6.96x10-6 | ||
| abnormal coat/hair pigmentation | 3 supporting datasets | Pfasem1(IMPC)J | heterozygote | Early adult | 4.87x10-7 | ||
| decreased circulating triglyceride level | 1 supporting dataset | Pfasem1(IMPC)J | heterozygote | Early adult | 6.97x10-5 | ||
| decreased circulating aspartate transaminase level | 1 supporting dataset | Pfasem1(IMPC)J | heterozygote | Early adult | 8.54x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pfasem1(IMPC)J | homozygote | Early adult | N/A * |
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External links
No external links available for Pfas.
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| Pfasem1(IMPC)J | Exon Deletion | | mouse |
| Pfastm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Pfastm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |