Trim58 | tripartite motif-containing 58

GeneMGI:2684862Synonyms: LOC216781, LOC386443

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Hematopoietic system Renal/urinary system

15 No significant impact

4 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetTrim58em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetTrim58em1(IMPC)MbphomozygoteEarly adultN/A * 
increased mean corpuscular volume1 supporting datasetTrim58em1(IMPC)MbphomozygoteEarly adult1.36x10-7 
enlarged lymph nodes1 supporting datasetTrim58em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetTrim58em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged kidney1 supporting datasetTrim58em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetTrim58em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Trim58em1(IMPC)MbpIntra-exon deletionmouse
Trim58tm102542(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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