Lrsam1 | leucine rich repeat and sterile alpha motif containing 1

Physiological systems

10 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Vision/eye Cardiovascular system

7 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased prepulse inhibition1 supporting datasetLrsam1em1(IMPC)BayhomozygoteEarly adult7.45x10-7 
eye hemorrhage1 supporting datasetLrsam1em1(IMPC)BayhomozygoteEarly adult6.65x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lrsam1em1(IMPC)BayInter-exon deletionmouse
Lrsam1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Lrsam1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Lrsam1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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