Zc3h4 | zinc finger CCCH-type containing 4

GeneMGI:2682314Synonyms: Kiaa1064-hp, Bwq1, +1 more

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Pigmentation Integument Embryo Nervous system Vision/eye Mortality/aging Cardiovascular system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal epididymis morphology	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Zc3h4^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
abnormal coat/hair pigmentation	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	heterozygote	Early adult	1.14x10^-6
hemorrhage	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
embryonic lethality prior to organogenesis	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal eye morphology	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
spina bifida	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	heterozygote	E15.5	N/A ^*
increased circulating serum albumin level	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	heterozygote	Early adult	4.39x10^-5
enlarged epididymis	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
prenatal lethality prior to heart atrial septation	1 supporting dataset	Zc3h4^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Zc3h4.

Associated images

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Histopathology

There is no histopathology data found for Zc3h4.

IMPC related publications

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External links

No external links available for Zc3h4.

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*Zc3h4^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Zc3h4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse

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