Cspp1 | centrosome and spindle pole associated protein 1

GeneMGI:2681832Synonyms: 2310020J12Rik, 4930413O22Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Pigmentation Integument Behavior/neurological Skeleton

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal locomotor behavior1 supporting datasetCspp1em1(IMPC)JhomozygoteEarly adult8.24x10-5 
abnormal vocalization1 supporting datasetCspp1em1(IMPC)JhomozygoteEarly adult4.45x10-9 
abnormal coat/hair pigmentation1 supporting datasetCspp1em1(IMPC)JhomozygoteEarly adult1.06x10-10 
decreased bone mineral content1 supporting datasetCspp1em1(IMPC)JhomozygoteEarly adult2.69x10-5 
decreased circulating creatinine level1 supporting datasetCspp1em1(IMPC)JhomozygoteEarly adult1.75x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cspp1em1(IMPC)JExon Deletionmouse
Cspp1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Cspp1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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