Wdr81 | WD repeat domain 81

GeneMGI:2681828Synonyms: shakey 5, MGC32441, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Behavior/neurological Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/ hair morphology1 supporting datasetWdr81em1(IMPC)JheterozygoteLate adult2.02x10-5 
decreased grip strength2 supporting datasetsWdr81em1(IMPC)JheterozygoteEarly adult8.76x10-5 
preweaning lethality, complete penetrance1 supporting datasetWdr81em1(IMPC)JhomozygoteEarly adultN/A * 
abnormal vocalization1 supporting datasetWdr81em1(IMPC)JheterozygoteLate adult1.43x10-7 
abnormal startle reflex1 supporting datasetWdr81em1(IMPC)JheterozygoteLate adult5.15x10-7 
increased blood urea nitrogen level1 supporting datasetWdr81em1(IMPC)JheterozygoteLate adult1.91x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Wdr81em1(IMPC)JExon Deletionmouse

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